Quartet handed first call-ups
England Under-21 coach Stuart Pearce has called four new players into his squad for the friendly against Uzbekistan at Ashton Gate on August 10.
The Uzbekistan game is England's only warm-up leading into their European Championship qualifiers agains Portugal and Lithuania in September.
Pearce confirmed Henderson would have been involved in the Under-21s last season had injury not intervened.
As well as four newcomers there are also notable omissions, which could provide a pointer towards Fabio Capello's thinking ahead of England's senior international against Hungary the following day.
Newcastle's latest recruit Dan Gosling is also missing, although Everton's highly-rated midfielder Jack Rodwell, who has tipped for senior honours in the near future, has been retained in the Under-21s.
The Under-21s lost to Greece in March and need to beat both Portugal and Lithuania to qualify for the play-offs.
"We're looking forward to playing again after sitting on a defeat for five months. The defeat to Greece put us in a difficult position in the group so we need to be ready," said Pearce. "It's given us a lot of planning time, so to have a friendly next week is great for us. Going into two important, must-win games next month without this game first would be unthinkable."
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