John Terry will miss England's friendly with France on Wednesday through injury, according to Chelsea manager Carlo Ancelotti.
Terry missed Sunday's stunning 3-0 home defeat to Sunderland after suffering a nerve problem in training that is leading to pain in a gluteal muscle and hamstring. And after the game Ancelotti said the defender would not be fit to play at Wembley, although he hopes to have him back for next Saturday's trip to Birmingham.
"Terry trained Saturday but, at the end of the training session, he had pain on his nerve in his hamstring and we had the test Sunday morning. He was not able to play. I don't think he will be able to play for the national team. He is out of the squad," said Ancelotti.
"I don't know if he has to report, we will wait to hear from them.
"He has had control of this problem. He never missed a training session but Saturday the pain was more, so he was not able to play.
"But I think he can play the next game. It is an injury, but he can control it. He has controlled it for 12 games. He's doing good prevention, good treatment. Everything will be okay for him."
England boss Fabio Capello has plenty of cover in central defence with Everton's Phil Jagielka having impressed in his recent international outings.
Other injury doubts are Andy Carroll and Gabriel Agbonlahor, who both picked up injuries playing for their clubs yesterday. Carroll will be assessed by England's medical staff Sunday night, with a groin injury threatening to ruin his chances of making his international debut against France.
The 21-year-old Newcastle striker received his maiden call-up to Capello's squad, but his involvement could now be limited to less than a day after the injury he picked up in Saturday's 0-0 draw with Fulham. His club confirmed on their official website the player is to report for duty, where he will be looked at by the England team doctors.
West Ham striker Carlton Cole has already been called up as cover for Carroll and Aston Villa's Agbonlahor, who is also struggling with a knock picked up against Manchester United.