Sean O'Driscoll's men have only lost two of their last eight league matches at the Keepmoat Stadium, including Saturday's 2-0 defeat to Birmingham.
Midfielder Coppinger told the club's official website: "It should be an interesting game, obviously on the back of Saturday's defeat we are looking to bounce back and get three points.
"I think it's going to be tough. They lost at the weekend and will be looking at the league thinking they want to get automatic promotion, the play-offs, but anything can happen.
"They will come here hungry and wanting to win so it will be a difficult game regardless of whether they are hunting for promotion and we'll see what happens.
"I think Reading are a good organised team and I think Steve Coppell has done a fantastic job and they'll be looking to get back into the Premier League. They've got a few away fixtures coming up so they'll be looking to get on a good run and we'll be trying to stop them."