The Jamaica defender has suffered his third hamstring injury of the campaign, meaning he will miss the Wearsiders' fight for survival.
Out: Nyron Nosworthy (right) won't being trying any more tackles this season
He pulled out of Wednesday night's reserves game at Derby after a recurrence of the injury which has kept him out for nearly two months.
Sunderland are four points above 18th-placed Middlesbrough on 35 and should be able to find enough points to maintain their place in the top flight.
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