Former Southend frontman Hooper, who was prolific in the Iron's promotion-winning campaign last season, scored twice in the first half either side of Paul Green's equaliser.
The Rams fought back in the second half and Kris Commons' penalty restored parity before Martyn Woolford scored the winner nine minutes from time.
But it was the performance of Scunthorpe's strike pairing that inspired Adkins' side, who showed an excellent response to their 4-0 drubbing at Cardiff on the opening day.
Adkins said: "I thought Paul Hayes and Gary Hooper were a massive threat all the way through.
"The team compliments them and it's great we have ammunition from quality midfielders who can pass the ball and we are trying to keep that as strong as possible, they have all got to compliment each other."
Adkins fears the performance of his strike duo could make it hard to keep hold of them in the transfer window.
He added: "It's not long before the transfer deadline so it will be an interesting time. I must admit, you look at Hayes and Hooper there today, there is bound to be people banging on the door after that performance."
The Scunthorpe boss was thrilled with the performance of his players, but warned supporters not to get carried away.
He said: "It is going to be a roller coaster ride, there are going to be ups and downs.
"We have not got to get too low when things go against us and enjoy things when they go well but don't get carried away."
Rams boss Nigel Clough bemoaned his side's defending as they were run ragged by Hooper and Hayes.
The former Burton manager felt his players were naive in pressing for the victory in an improved second-half showing.
He said: "We've come back from 1-0 down and 2-1 down, then we should be protecting the point that we've got.
"We have got experienced players out there who are thinking of going on and winning the game instead of ensuring we didn't lose.
"We are disappointed with the manner in which the back four failed to deal with them (Hooper and Hayes). We just didn't deal with it well enough, we were on the back foot, didn't get tight and it's caused us problems."
He added: "The fact we're scoring goals is always a good sign, but the problem we've got is that it shouldn't be at the expense of conceding at the other end."