Griffiths joined the Championship side on Friday after passing a medical.
Midfielder Danny Spiller is still out with a hamstring injury but striker Josh Scott will return after recovering from an ankle injury.
Jon Nurse will keep a place in the side but will move back to midfield with Tommy Tejan-Sie back on the bench.
Forward Wesley Thomas will retake his place on the bench after a bout of flu ruled him out of the 2-1 win over Bradford last weekend.
Long-term absentee Mark Nwokeji is back in training following his cruciate knee injury but is unlikely to be included in the first-team squad until December.