Steven Gillespie is pushing for his first start of the season when Colchester travel to promotion rivals Huddersfield.
The striker, Colchester's record signing, put an injury-hit campaign behind him when he scored twice as a substitute in last week's 2-1 win over Bournemouth.
Boss John Ward could also add recent signings Conor Powell and Matthmas Vilhjalmsson to his squad now that they have a weeks' training under their belts.
Ben Coker made his full debut at left-back against the Cherries and looks set to keep his place after an impressive display.
Defenders Magnus Okuonghae, Brian Wilson (both ankle) and Morten Knudsen and midfielder John-Joe O'Toole (both knee) are still on the sidelines.