Chile captain Claudio Bravo insists they have the weapons to beat Brazil and secure World Cup qualification.
They may have never won a qualifier on Brazilian soil but the Manchester City goalkeeper remains confident they can achieve what no other side has managed in the current campaign.
Brazil have already guaranteed their participation in Russia next summer - the only South American country to do so heading into the final round of matches - and have dropped just two points out of a possible 24 at home so far.
The situation is so tight in the group that a draw or a defeat could see Chile, who are currently third, end up with an automatic qualifying spot, finish fifth and go into the play-off with New Zealand or get knocked out altogether. Bravo, though, insists they are focused on one outcome only.
"We're not worried about the other games. All we're thinking about is picking up points in Brazil," Bravo told a press conference.
"We have to beat a strong opponent, who are playing at home, and I think we have the weapons for it.
"We have players and selection to do harm. We are also the ones who improved in the last game (Chile beat Ecuador, whereas Brazil drew in Bolivia).
"We will play our game and try to make history."
Bayern Munich midfielder Arturo Vidal is suspended with possible replacements Charles Aranguiz and Pablo Hernandez both injury doubts.
Bravo's Manchester City team-mate Gabriel Jesus, the Brazil striker, has more reason than most to want to put on a good show in his nation's final qualifier.
The match is being held at Allianz Parque, the home of his former side Palmeiras and where he played his final match for the club almost a year ago before moving to England.
"For me it's the perfect scenario for us to finish our run in the qualifiers," he said.
"It's very special to play at Allianz. When I step out there I will remember that day but we have to play seriously.
"The qualifiers were my first matches for the national team. It's been sensational and I am happy with my current situation but I have to keep working, keep running, fighting and doing what I always did to keep my place.
"I'm better than last year. I am evolving more and more as a professional.
"I've been dreaming of the World Cup since I decided to be a footballer so I'll fight to earn it it."