The Premier League clash at Old Trafford could prove pivotal in deciding the outcome of the title race. And Ferdinand admits that United are determined to prove against Chelsea that the Bayern performance was a one-off.
Related ArticlesAncelotti: United are better off without RonaldoManchester United v Chelsea: previewBerbatov can seal United placeDefoe backs Berbatov to shineFerguson: Rooney could be back in two weeksSport on televisionHe said: "Losing to Bayern was difficult to take, but you don't get everything you want, or your own way. Over the last couple of years we've become accustomed to dealing with things and grinding out results, but against Bayern we didn't manage to do that.
"It's part and parcel of football. You lose one, you dust yourself down and get on with it. That's what we'll do against Chelsea. That's what this club is about. We don't like losing. But you have to take some things on the chin and get on with it, and I'm sure on Saturday you'll see a much better, brighter team."
The loss of 34-goal top scorer Rooney could ultimately scupper United's push for domestic and European glory, but Ferdinand is confident that Sir Alex Ferguson's team can overcome the loss of their talisman.
He said: "In the games Wayne has missed recently, we've scored goals. Dimitar Berbatov has come in and has done ever so well. Wazza [Rooney] is a great player and obviously has been very influential, but we have got players who when they come in, can do it.
"The Chelsea game is crucial, though. Every game now until the end of the season is like a cup final. It's a cliche but a fact.
"We didn't defend as well as we should have done against Bayern and will have to be better against Chelsea."