Spain boss Vicente del Bosque has left Chelsea's Fernando Torres and Juan Mata out of his squad for the World Cup qualifier against Finland.
Neither player was included for the recent friendly against Ecuador, and with Torres and Mata unable to earn permanent places in Chelsea manager Jose Mourinho's early team selections there has been no recall for the pair.
Manchester United goalkeeper David De Gea is also again out of favour, with Del Bosque staying faithful to Iker Casillas, Jose Reina and Victor Valdes.
Atletico Madrid midfielder Koke keeps his place, having been a surprise choice last time, as do Real Madrid new-boy Isco and Real Sociedad defender Inigo Martinez.
Coming back in after missing out last time are Barcelona midfielder Xavi and Atletico striker David Villa, while Villa's club-mate Mario Suarez is handed a chance to impress.
World champions Spain play Finland in Helsinki next Friday, defending top spot in Group I, and have a friendly against Chile on the following Tuesday.
Spain squad for World Cup qualifying match against Finland on September 6 and friendly against Chile on September 10:
Iker Casillas (Real Madrid), Jose Reina (Napoli), Victor Valdes (Barcelona); Alvaro Arbeloa (Real Madrid), Koke (Atletico Madrid), Raul Albiol (Napoli), Sergio Ramos (Real Madrid), Inigo Martinez (Real Sociedad), Jordi Alba (Barcelona), Ignacio Monreal (Arsenal), Santiago Cazorla (Arsenal), Sergio Busquets (Barcelona), Mario Suarez (Atletico Madrid), Xavi (Barcelona), Andres Iniesta (Barcelona), Jesus Navas (Manchester City), David Silva (Manchester City), Alvaro Negredo (Manchester City), Roberto Soldado (Tottenham), Pedro (Barcelona), David Villa (Atletico Madrid), Isco (Real Madrid), Cesc Fabregas (Barcelona).