Chelsea and West Ham cruised into the FA Cup quarter-finals on Sunday but Tottenham crashed out at home to London rivals Crystal Palace.
An unlikely goal on a rare start for Martin Kelly, coupled with a vastly improved overall performance, proved enough to secure Alan Pardew's Palace a 1-0 win at White Hart Lane which ended Spurs' treble hopes.
Chelsea's hopes of ending a miserable season at Wembley remained alive and well, meanwhile, as the Blues beat a much-changed Manchester City side - featuring five full debutants - 5-1 at Stamford Bridge.
Willian, Gary Cahill, Eden Hazard and substitute Bertrand Traore scored second-half goals to extend Guus Hiddink's 100 per cent record in the competition to six games.
And West Ham's talisman Dimitri Payet was the inspiration as they ran out comfortable 5-1 winners at Blackburn.
Rovers, who played the last 35 minutes with 10 men after Chris Taylor's sending-off, had led through free-scoring right-back Ben Marshall in the 20th minute but were pegged back six minutes later by Victor Moses' first goal since September 19.
An exquisite Payet free-kick followed and two second-half goals for Emmanuel Emenike before Payet fittingly finished things off with a brilliant individual effort.
Taylor's dismissal for a second yellow card was balanced out by a straight red shown to Cheikhou Kouyate 15 minutes from time for denying Blackburn left-back Adam Henley a goalscoring opportunity, but it had no impact in altering the momentum.
Chelsea will travel to Everton in the pick of the last-eight ties, with Palace drawn at Reading, and West Ham facing a trip to Shrewsbury or Manchester United.
Source: PA-WIRE
