Rae, 31, and forward Dorrans, 22, have been drafted in after James McFadden and Callum Davidson were ruled out of the final Group Nine match through suspension and injury, respectively.
Celtic's Scott Brown is also a doubt for Wednesday night, with an ankle injury.
Dorrans has not played for Scotland before but has represented his country at under-21 and under-20 level.
Terry Butcher insists everyone must now move on after the Scottish Football Association were told there was no hope of appealing McFadden's yellow card and the Scotland assistant manager challenged others in the squad to fill the void.
He said: "We contacted FIFA but that's it as far as they are concerned. There is no appeal, the booking stands and Faddy doesn't play on Wednesday. We draw a line under that now and we have to move on.
"There are a couple who aren't available to play on Wednesday so we have added Graham Dorrans and Gavin Rae to the squad so that gives us more bodies and options in midfield.
"It's an opportunity for other people to step in and, if they can, try to fill Faddy's shoes."
McFadden was cautioned following a melee which was sparked by Brown winning a corner at a drop ball, rather than returning possession to Macedonia.
Asked if the booking was avoidable, Butcher replied: "I've had some ridiculous bookings in the past as well.
"This one was a situation where there was a melee with Scott Brown and everyone else and it was pleasing to see our players trying to protect Scott because he looked like he was in Land of the Giants with all those big Macedonians around him.
"Sometimes you get caught up in it and the referee is under pressure to take action and flash the cards and control the situation.
"I think it was the assistant who helped in terms of getting Faddy booked but it's gone now and we move on from it.
"It's desperately disappointing for Faddy and the country and the team but there are other players who want to prove a point."
George Burley revealed yesterday that Brown's injury was not as bad as first feared and the player, himself, is optimistic of being involved against the Dutch.
Butcher said: "Scott Brown is confident of playing but I think he would be confident even if he had a broken leg. He is confident and, if he's confident, that augurs well. That's a real boost for everybody."