"We're really looking forward to it," he told the club's official website, www.cardiffcityfc.co.uk
"It's a nice ground and a big pitch, which should suit us, so we're confident and hopefully we can put our chances away this time and get a result."
Johnson, an ever present in boss Dave Jones' side this term, admitted Cardiff may have missed their best chance of progressing when they failed to find the net at Ninian Park.
He continued: "We'll go there and, as we do in every game, try and get a result. We probably should have taken a couple of the chances in the first game as we had the more clear-cut efforts.
"It was disappointing not to get the result and we may have shot ourselves in the foot but we'll try and do out best to keep a clean sheet and nick a goal."
Cardiff are looking to emulate the unlikely run that saw them make the final of last year's competition, where they lost 1-0 to Portsmouth.
However, Johnson is fully aware the task of seeing off Wenger's side will be just as challenging as any of the ties they faced last season.
"Arsenal are always tough," he conceded. "The FA Cup is always different to the league and it's all about on the day, where they are capable of beating anyone.
"Sometimes they let you have the ball and sometimes they don't. The movement is a lot quicker and, for me as a centre-half, the runs they were making were different in the last game to what I am used to week in, week out.
"We expect a tough game regardless of their league form, and we will try and do what we have done well this season."
Arsenal will be missing the injured Emmanuel Adebayor and Johnson is hopeful the loss of the Gunners' influential striker will aid Cardiff's quest.
"They have depth and quality in their squad but Nicklas Bendtner and Robin van Persie played in the last game and we handled them well so there is no reason why we can't do it again," he said.
Johnson's confidence is underpinned by Cardiff's sterling form this term - they are currently fourth in the Championship table with games in hand and have not lost since November.
That record has created a winning mentality at the club and Johnson is hoping Cardiff's fans, of whom 9,000 are expected to travel, can make a difference.
"I'm sure they will make a lot of noise," he added. "Hopefully Arsenal will see it as a big game and pack the place out, and we can do as well as we did in the first game."
, Draw 10/3
, Cardiff 9/1