Cambridge will be without the suspended Uche Ikpeazu when they welcome Newport to the Abbey Stadium on Saturday.
Ikpeazu was sent off in the closing stages of last weekend's 2-0 defeat at Port Vale after picking up two late yellow cards.
Ade Azeez could come into the side having come off the bench against Vale following three months out with a calf injury.
Gary Deegan (foot) is expected to miss out once more and David Amoo could also be absent after getting injured in the FA Cup defeat to Newport a fortnight ago.
Newport are set to be boosted by the return of Ben Tozer.
The midfielder missed last week's thrilling 3-3 home draw with Carlisle through illness.
Defender Scot Bennett is also in contention after sitting out the last two games with a hip problem.
Calaum Jahraldo-Martin and Marlon Jackson remain out with hamstring injuries.
Source: PAR