Paul Lewis set for Cambridge bow
Paul Lewis is looking to make his debut when Cambridge welcome Mansfield in Sky Bet League Two.
The 22-year-old former Macclesfield midfielder was an unused substitute in the 0-0 draw with Blackpool last weekend but is pushing for a start.
Defender Scott Wharton, signed on loan from Blackburn, will also be considered by manager Shaun Derry.
Blair Adams could start at right-back if Brad Halliday (knee) does not pass a late fitness test but Greg Taylor (groin) is definitely out.
Shaq Coulthirst should be added to the Mansfield squad after joining the club on loan but Chris Clements has left to join Grimsby.
Forward Coulthirst moved to the One Call Stadium from Peterborough on Thursday and Stags boss Steve Evans is trying to sign another unnamed player from Posh ahead of the trip.
Kyle Howkins is still nursing the knee injury he sustained during the Checkatrade Trophy victory over Oldham and he remains out.
The only other absentees are fellow defenders George Taft and Corbin Shires, who continue to work on their rehabilitation from respective hamstring and knee injuries.