Darren Moore will serve a one-match suspension when Burton host Oxford in the FA Cup first round on Sunday.
The experienced centre-half collected his fifth yellow card of the season during the league stalemate against Port Vale, and also aggravated a hamstring injury.
Moore's absence coincides with the timely return of Tony James from his month on loan at Hereford. James is unlikely to make the starting line-up, but he will provide much-needed defensive cover with Richard Jackson and Paul Boertien (calf) on the injured list.
Manager Paul Peschisolido may also be forced to rest the versatile Aaron Webster. Operating in a new role behind the strikers, Webster was a surprise inclusion against Vale on Tuesday night as he had been struggling with a calf injury - and he is back on the treatment table.
"Aaron's calf tightened up again and he also got a dead leg, so he is a doubt for Sunday," said Peschisolido.