The Pirates are third in League One after winning six of their first eight games and made it three consecutive victories by seeing off Brentford 3-1 last weekend.
Chris Dickson marked his debut by scoring twice against the Bees following his loan move from Charlton and should make his home debut.
Dickson is likely to partner Jo Kuffour in attack, with Darryl Duffy remaining on the bench.
Former Derby defender Steve Elliott is also expected to be in the bench, with the Pirates having conceded just one goal in their last four games.
One player that will definitely not feature is midfielder David Pipe, who has been suspended by the club after being arrested on suspicion of assault.