New signing Jerel Ifil will be in the Bristol Rovers squad for the first time when Dave Penney takes his team to Brentford.
The 28-year-old defender has signed on non-contract terms until the end of the season following his release from Scottish Premier League side Aberdeen and will go straight into the squad to face the Bees.
However, fellow defender Carl Regan has joined Notts County on loan, linking up again with his former Macclesfield and MK Dons boss Paul Ince for the third time.
Centre-back Dave McCracken is doubtful with a hamstring problem, while midfielder Stuart Campbell will miss out again with a similar injury.
Recent signings Conrad Logan and Danny Senda are set to retain their place in the starting line-up following good contributions to last weekend's 1-0 win over Oldham.
Goalkeeper Logan kept a clean sheet following his arrival from Leicester and full-back Senda played his first full 90 minutes in over two years following a serious knee injury.