Borussia Monchengladbach are seeking to spark their season into life when they play in Europe's elite club competition after a 37-year wait at Sevilla.
The German club went into this summer on a high after finishing third in the Bundesliga to qualify for the Champions League group stages, but they have lost four straight games at the start of the new domestic campaign and have conceded 11 goals while scoring just two in the process.
Friday's 3-0 loss to Hamburg left Lucien Favre's side with no points and at the foot of the Bundesliga standings heading into their Group D opener in Spain.
"We're all very excited for the Champions League," Monchengladbach left-back Oscar Wendt said on his club's official website. "We've got a brilliant, but also tough game ahead of us.
"It's up to us to finally find our form again."
Monchengladbach have lost only two of their last 10 European away games, including a 1-0 defeat at Sevilla in last season's Europa League round of 32 first-leg encounter.
Sevilla won all seven of their home European ties last season en route to lifting the Europa League trophy and have yet to lose against a Bundesliga side at the Ramon Sanchez Pizjuan stadium.
They finished fifth in La Liga last term but qualified for the group stages after a successful Europa League title defence.
Like Tuesday's opponents, the Andalusian club has endured a slow start to the campaign.
Sevilla lost 5-4 in extra-time to Barcelona in last month's UEFA Super Cup encounter in Tbilisi, Georgia, and have taken just two points from their opening three games in La Liga.
Unai Emery's side scored their first league goal of the season in Friday's 1-1 draw at Levante.
"We've created plenty of chances to win games and I'm sure the goals will come," Emery said on his club's official website. "We want to be competitive in the Champions League but also be fighting in the high positions in La Liga.
"It's a challenge and we need to be efficient."
The hosts will not be at full strength on Tuesday with Portuguese goalkeeper Beto sidelined for six weeks with a knee injury. Sergio Rico will start in goal.
Defenders Daniel Carrico and Adil Rami are both sidelined with thigh injuries.
The visitors are without Swiss midfielder Granit Xhaka, who is suspended.
Monchengladbach captain Martin Stranzl is out with a fractured cheekbone while team-mates Fabian Johnson, Patrick Herrmann and Alvaro Dominguez are also injured.