Robert Lewandowski fired four goals as Borussia Dortmund emulated fellow Germans Bayern Munich's Champions League semi-final domination of Spanish opposition with a 4-1 win over Real Madrid.
The Poland striker gave Jurgen Klopp's men an early lead and, after Cristiano Ronaldo equalised late in the first half for Madrid, Lewandowski struck three times more in the second half.
Following 2012 finalist Bayern's 4-0 hammering of Barcelona on Tuesday, it was a further indication ahead of next week's return legs in Spain that the balance of power in European football may be shifting.
Dortmund started brightly as Marco Reus isolated Raphael Varane and surged through the visiting defence. His shot was parried by Diego Lopez and Lewandowski, reluctant to over-stretch, failed to tuck away the loose ball.
The opening goal arrived in the eighth minute, though, Mario Gotze swinging in a superb cross from the left for Lewandowski, this time reaching out a long right leg after losing his marker Pepe, to sidefoot home.
Real began to establish themselves in the game as the tempo settled down, and a 30-yard free-kick provided their first sight of goal. Ronaldo's dipping effort was beaten away by keeper Roman Weidenfeller.
Madrid were level as Gonzalo Higuain as he seized on Mats Hummels' poor back-pass and squared for Ronaldo to slot the ball home. That left the scores level at the break but Lewandowski restored his side's lead five minutes after the restart.
With Real appealing for offside as Reus' pass found the Pole he kept his head, turned quickly on the ball and poked low past Lopez.
And it was soon 3-1 as Marcel Schmelzer's mishit shot deflected to Lewandowski, who brilliantly dragged the ball back away from Pepe and fired it into the top corner.
And dominant Dortmund were then awarded a penalty for Xabi Alonso's blatant shove in the back of Reus. Lewandowski slammed the penalty straight down the middle to make it 4-1.