Champions League side Borussia Dortmund's injury worries have worsened with both Germany pair Marco Reus and Sven Bender out of Tuesday's German Cup quarter-final at Eintracht Frankfurt.
Left winger Reus suffered a torn right thigh in Saturday's 5-1 Bundesliga hammering of Werder Bremen and will be out for a fortnight, while defensive midfielder Bender has a thigh strain and misses the next week.
Frankfurt host Dortmund in the cup on Tuesday, then travel to Borussia's Westfalenstadion on Saturday for a Bundesliga match and Bender faces a race against time for the league clash.
The double injury blow is more bad news for Dortmund coach Jurgen Klopp who lost Germany defender Mats Hummels last week after the centre-back injured his foot in a friendly and will miss the Frankfurt double-header.
Klopp is already without both centre-back Neven Subotic and winger Jakub Blaszczykowski for the rest of the season as the pair have torn knee ligament injuries.
Dortmund are away to Zenit St Petersburg in the last 16, first-leg of the Champions League on February 25.