Adam suffered a medial ligament strain playing in Scotland's victory over the Faroe Islands on Tuesday and looks likely to miss out.
Ghana international Richard Kingson will continue in goal with Matt Gilks ruled out for up to two months with a broken kneecap. Youngster Mark Halstead has been recalled from a loan at Barrow as back-up.
Blackpool have no other new fitness concerns but are still missing long-term casualties Billy Clarke, Alex Baptiste and Louis Almond.
Blackpool manager Ian Holloway is looking forward to welcoming Mick McCarthy to Bloomfield Road tomorrow having cleared the air with his Wolves counterpart.
Holloway apologised to McCarthy over a misunderstanding which arose as the Tangerines boss tried to justify his controversial 10 changes at Aston Villa last week.
Holloway suggested McCarthy did not think he could win when he made wholesale changes for Wolves' visit to Manchester United last season.
Wolves were hit with a #25,000 suspended fine for fielding an understrength side in that match.
Blackpool could be subject to similar sanctions having been written to by the Premier League for an explanation for their team selection at Villa Park nine days ago.
Holloway intends to mount a robust defence of his actions - and has threatened to resign if fined - and is sorry for dragging McCarthy into the controversy.
Holloway claims he commented on the Wolves case without knowing the full facts when asked in his post-match press conference immediately after the game at Villa, which his side lost 3-2 to a late goal.
"He was unhappy with what I said - I have never been unhappy with Mick," said Holloway at another press conference.
"I didn't know what Mick said. One or two of you people [media] told me Mick said something and I responded to it.
"Mick did what he felt was right and I don't think she should have been fined.
"Mick is a great manager - if I even do half of what he has done I will be delighted. Mick and I haven't got a problem.
"But that story has gone, let's move on. I am just getting on with my team for Wolves - it's quite ironic that we play Wolves next."
Holloway respects the achievements of former Sunderland and Republic of Ireland boss McCarthy and feels Wolves' current lowly position in the Barclays Premier League is no reflection of their ability.
Wolves go into the game 19th in the table with just nine points from 13 games, six behind Blackpool.
Holloway is also surprised the Molineux side appear to have acquired a reputation for dirty play this season.
"Again that is an absolute load of poppycock," the Seasiders manager said. "They are a fantastically hard-working team.
"They play great football, they stayed up last year and they'll be desperate to stay up again this year.
"They had a great start last year and everyone was saying how great they were.
"Now all of a sudden a few borderline tackles have been highlighted and blown out of all proportion."
Wolves defender Christophe Berra is set to return.
The Scotland defender was forced to withdraw from last weekend's home defeat against Bolton shortly before kick-off with a sore knee.
Fellow centre-back Steven Mouyokolo has also been declared fit after suffering a knee injury in the early stages against the Trotters although he was able to complete the game.
Winger Matt Jarvis is expected to be fit despite missing part of training this week with a calf injury.
McCarthy admits Wolves are approaching the "defining period" of the season, saying: "We are getting good at taking positives out of defeats and I am sick of it. It is wearing a bit thin.
"We've played well enough in all the games recently.
"We always take the positives out of any game but it is time to get three points.
"In games when you are playing teams, like we've got in the next six or seven games, you've got to get points.
"It is it a defining period up to Christmas. With the position we are in now, we've got to get results and wins and we have to get them quickly.
"We can't wait any longer for them."
McCarthy insists he does not suffer sleepless nights through Wolves' current plight.
He also knows there is no magic formula for reviving their fortunes but believes Wolves are due a change of fortunes.
McCarthy said: "I sleep fine. I am preoccupied at times, more so when you are not winning, because when you are winning, you can have a happy, normal existence."
Source: DSG
