The 24-year-old could be out for up to six weeks after suffering a recurrence of an old knee ligament injury.
Surgery: Baptiste will need to find out the full extent of his injury
His absence could see Wales international Neil Eardley, who was substituted at half-time at Chelsea last week, come in at right-back.
Manager Ian Holloway has no other new injury concerns but changes are possible following the 4-0 hammering at Stamford Bridge. Billy Clarke (knee) is a long-term absentee.
Team (from): Gilks, Keinan, Eardley, Taylor-Fletcher, Crainey, Evatt, Adam, Vaughan, Varney, Ormerod, Campbell, Grandin, Harewood, Southern, Carney, Cathcart, Basham, Euell, Sylvestre, Demontagnac, Coid, Husband, Phillips, Edwards, Halstead.
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