Stuart Parnaby is expected to replace Vignal if he is ruled out with record signing Christian Benitez a candidate to take over from Jerome should he fail to recover.
Midfielder Lee Bowyer returns to the squad after completing a three-match ban for his sending-off at Preston at the tail-end of last season.
Birmingham (from): Hart, Carr, Queudrue, Roger Johnson, Vignal, Larsson, Ferguson, Fahey, McFadden, Jerome, O'Connor, Maik Taylor, Phillips, Benitez, McSheffrey, Parnaby, O'Shea, Carsley, Bowyer, Damien Johnson.
Birmingham v Stoke. Click here to bet.