Birmingham cruised into the quarter-finals of the FA Cup for the second successive season but Alexander Hleb is facing Wembley heartbreak.
Hleb set up the first two goals for Jean Beausejour and Obafemi Martins but was then stretchered off and looks doubtful for next weekend's Carling Cup final against his former club Arsenal.
Full-back David Murphy scored the third goal early in the second period and Birmingham were comfortable 3-0 winners against Sheffield Wednesday despite making eight changes.
Martins, on loan from Rubin Kazan for the rest of the season, staked his claim to start against the Gunners with an impressive performance and he showed excellent movement.
Veteran midfielder Lee Bowyer also demonstrated his quality with some trademark runs into the Wednesday box while Keith Fahey also caught the eye in a defensive central role.