Callum Crane and Sandy Cunningham out for Berwick
Berwick host League Two winners East Fife without Callum Crane and Sandy Cunningham.
Crane is suspended and Cunningham has a dislocated shoulder.
Boss John Coughlin said: "We are on a very good run and won at Arbroath last weekend however we did not play well. We need to lift our game for the visit of East Fife as beating them would be a huge feather in our cap.
"They are a good side and deserve to have won the league. They will not be wanting their season to end on a low so we need to play much better than we did last weekend to win."
The Champions have everyone fit and available with player-manager Gary Naysmith insisting his side will not be slowing down despite their success.
Naysmith said: "We enjoyed winning the league last Saturday at Clyde and we will enjoy a party next weekend when we get the trophy, but we are still looking to win games.
"We simply have to play well to win this game as Berwick's form recently has been good enough to be title challengers and they will see this as a good opportunity to put down a marker for next season.
"I want us to finish on 67 points so we will look to win."