Bayern Munich expect Philipp Lahm to miss up to three games following a fracture to a bone in the full-back's foot.
The Germany international limped out of Tuesday's 3-0 Champions League victory over Fiorentina.
"We hope it's not too drawn out, but we're counting on being without him for the next two or three matches" revealed coach Jurgen Klinsmann.
Lahm himself added: "I'm assuming I'll be playing again before the winter break, although we haven't had the final diagnosis yet.
"It's a shame when you're forced to take a break, but it's not come as a shock. I've had much worse."