Barnsley's summer signing Jim O'Brien could make his first competitive appearance for the club against Crystal Palace.
But the Tykes will be without defender Stephen Foster, sidelined for seven days as a precaution after sustaining concussion in midweek.
Former Motherwell winger O'Brien, who signed a pre-contract agreement in May, has been struggling with a thigh injury and missed the opening-day defeat at QPR and Tuesday's Carling Cup upset against Rochdale.
Manager Mark Robins could recall striker Andy Gray and winger Martin Devaney to his starting line-up after both started on the substitutes' bench against Rochdale while Iain Hume will also be hoping for a recall.
Recent signing Jeronimo Neumann was omitted from the squad in midweek after appearing as a second-half replacement at QPR while Robins has vowed to make further changes after seeing his side make a disappointing start to the season.