O'Flynn scored 18 league goals last season but missed the start of this campaign with a foot injury.
However, he came off the bench to score his first goal of the season in the 3-1 win at Northampton last Friday and is set to start alongside Paul Furlong at Moss Rose.
Hendon is set to stick with the rest of his starting XI which won convincingly at Sixfields and put the Bees briefly at the top of League Two.
Defender Dan Leach remains sidelined with an ankle injury and his latest scan has shown that he will be out for another fortnight.
Assistant manager Gary Breen is still out with a knee problem but left-back Kenny Gillet recovered from his hamstring injury to be named on the bench last time out.