The Dutchman insists that is normal practice before every game his teams play as he goes over every potential pitfall in his head.
The Blues' temporary boss also admits playing right-back Jose Bosingwa on the opposite side to fill the hole left by Ashley Cole's suspension is his biggest headache.
Bosingwa will be pitted against Lionel Messi in the first leg of the Champions League semi-final, a 'complex' task according to Hiddink.
Hiddink told The Sun: "You have to think ahead and I have played Barcelona twice in my head.
"In my head, I have never lost a game in preparation. But you have to focus a lot on the difficulty and the complexity of the job Bosingwa has to do.
"In my opinion, Bosingwa is playing one of the most attractive players in the world."
The Russian says playing against Barcelona is a lot different to playing the likes of Manchester United and Liverpool in the Premier League.
"Although they like to attack, we like to attack as well, but when you play Manchester United or Liverpool, it is a less controlled game and can go either way. Like pinball," he added.
"When you play Liverpool or United or they play us, the pace of the game can go up any second. Boom.
"But Barca are very smart. They can turn the pace of the game up or down. You think you are in control and then all of a sudden they strike.
"They are skilful and have very good possession and can frustrate a team by having possession.
"We must not get frustrated. If they score then we must have the confidence that we can score at any moment."