FIFA have set aside just one date for international matches before the end of the European season - March 3 - but the United States have announced they will face Honduras on January 23 and are also understood to be planning to play Mexico a month later.
Eight England-based players have been recently called up by Bob Bradley and will hope to stay in the head coach's plans in the run-up to next summer's finals.
American dreams: Jozy Altidore (right), Tim Howard (left) and Clint Dempsey are hoping to go to the World Cup
The match against Honduras in Los Angeles comes at the end of a training camp that is expected to be mostly made up of North America-based players.
But, particularly for the Mexico match, there may be pressure for more senior players to seek permission to play.
Tim Howard (Everton), Brad Guzan (Aston Villa), Marcus Hahnemann (Wolverhampton Wanderers), Jonathan Spector (West Ham United), Jozy Altidore (Hull City), Eddie Johnson, Clint Dempsey (both Fulham) and Jay DeMerit (Watford) are all hoping to go to the World Cup.
The US have been drawn against England, Slovenia and Algeria in Group C at South Africa 2010.
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