The pair did not even make the bench for Saturday's 5-0 demolition of Portsmouth, which suggests they will face Martin O'Neill's men.
Experience: Old head Giggs (left) is set to face Aston Villa
Rio Ferdinand is suspended, while Nemanja Vidic has an outside chance of being involved for the first time this year after suffering a nerve problem in his leg last month.
Team (from): Van der Sar, Kuszczak, Neville, Brown, Rafael, De Laet, Vidic, Evans, Evra, Fabio, Park, Nani, Valencia, Carrick, Scholes, Fletcher, Gibson, Anderson, Giggs, Rooney, Owen, Berbatov, Diouf.
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