The 18-year-old Arsenal midfielder has been selected by Fabio Capello for Wednesday's friendly with Hungary at Wembley, which represents a meteoric rise for a player who spent half of last season on loan at Bolton.
Wilshere will become the 10th-youngest senior England international of all time if he makes his bow against the once-mighty Magyars.
But he will not let the prospect go to his head when he links up with his new team-mates at their Watford base tomorrow night.
"I am delighted to have been named in the England squad for the first time," he told www.arsenal.com.
"It is a real honour and I'm looking forward to the experience. But I am also realistic and want to take things one step at a time.
"Being called up to the England squad is a proud moment for me and my family, but my first target is to break into the Arsenal team and play on a regular basis.
"To achieve that, I need to keep my head down, work hard and stay focused."
The same sentiments could also apply to Theo Walcott, who has been recalled, and Kieran Gibbs, who becomes a third Gunner to be included.
It is a remarkable effort from Arsene Wenger, who has so often been criticised for his failure to develop young English talent.
And for Gibbs, it represents adequate reward for the patience he has shown in battling back from the injury he suffered last November that ended his outside chance of making it to South Africa.
"It's a welcome surprise to have been called up by Fabio Capello to the England squad for the first time," said the 20-year-old.
"It is always an honour to play for my country at any level but it is a special moment to be called up to the first-team squad.
"To reach my full potential, it's important that I keep on improving all aspects of my game and this call-up will certainly be a great learning experience for me. I just want to make the most of every opportunity I am given to better my game.
"I have to say this a real boost for me as I spent over five months out through injury and this is a good opportunity to thank the surgeons and medical support I've received to get me back to full fitness.
"Naturally my top priority at this moment in time is to get back to the level I was at before my injury and get some games under my belt with Arsenal, but of course, I would love to cement a place in the England team in the future."