Wayne Rooney has been installed as the overwhelming favourite to land the award following the release of the short-list on Thursday.
The Manchester United star has enjoyed an outstanding season, even if it appears his success at club level will be limited to the Carling Cup. Like Rooney, Fabregas has been selected for both the main award, and the young player of the year prize.
Although he has been sidelined for the rest of the season by injury, Fabregas held together a Gunners' title challenge that twice seemed to have collapsed before Tottenham almost certainly snuffed it out on Wednesday night.
As champions-elect, Chelsea were bound to have a representative, and while he might not have hit the heights as consistently as in other years, Didier Drogba's goals ensured the Stamford Bridge outfit came through their rocky patch and are now in line to become only the seventh team to land the domestic double.
Manchester City's emergence as a Premier League force is also confirmed by the presence of Carlos Tevez, who has been such a pivotal figure for the Blues since his controversial summer move from neighbours United.
Along with Rooney and Fabregas, Birmingham's on-loan Man City goalkeeper Joe Hart and Aston Villa midfielder are also up for the young player award.