"I've played in some fantastic stadiums in my short career so far. But winning here would top the lot," he said.
Related ArticlesGuardiola still setting the standardArsene Wenger believes Arsenal can rise againWalcott's pace impresses BarcaSong out of Barcelona clashBarcelona v Arsenal: match previewInjury worries mount for Barcelona"I would love to be part of the team that won here, and to win in Barcelona you have to believe you can do it. We've got to believe we can get a result.
"There are big players missing but we've got to come here and do a job - that's all we can do."
The Spanish media have dubbed Walcott as the biggest threat to Barcelona progressing to the final four of this year's competition, and the England international is hoping his pace will cause just as much upset this week as it did last week.
"We have scored a lot of late goals, especially in the Premier League, and we believe we can do it again here," he continued. "As a winger you have to be on the front foot. Hopefully I can get at them and produce a problem.
"Barcelona at times played some fantastic football but they died in the last 20 minutes."
Barcelona manager Pep Guardiola praised Walcott after the first leg, but insisted he was not the reason the Spanish side lost their 2-0 advantage.
"Let's be clear, Walcott was not the determining factor, the determining factor was Almunia, who saved 12,000 balls," the 39 year-old said.
"Walcott is so speedy, he has strong legs, he played very well against us (on Wednesday) and also in the last league game," he said.
"But we will try to keep the ball, that's the best way to stop Arsenal and to stop Walcott as well."