Rory Boulding is set to hand Accrington a boost ahead of their trip to Northampton.
The striker missed the midweek Carling Cup win over Championship side Doncaster after picking up an ankle knock in the opening day draw against Aldershot.
However, Boulding is expected to return to contention, leaving manager John Coleman with a full squad at his disposal.
Coleman will be keen to keep changes to a minimum following his side's impressive performance on Tuesday night, although one or two players may well be rested after completing 120 minutes at the Keepmoat Stadium.
Winger Chris Turner will be hoping to feature from the start after coming off the bench to grab his side's first goal against Doncaster.